We imagine it would be hard to say “no” to Bono, but then again, we’re not the industrial design geniuses (Sir) Jonathan Ive and Marc Newson. Neither of these men require an introduction. (We’ll do it anyway.) Jonathan Ive is the senior vice-president of design at a little technology company called Apple Inc., while Mr. Newson’s acclaimed designs have touched everything from aircraft to bicycles, cameras to furniture. Newson is also an avid driver, and races the Mille Miglia yearly.

Collaborating with Bono and Bobby Shriver for the (RED) charity, Ive and Newson have personally curated a collection that celebrates the best in design and innovation. The collection is so impressive that a highlight reel might simply include all 40 works. If you appreciate design, engineering, space, music or style and are itching to liquidate your family’s trust fund, then ready your paddle.

This auction is expected to reach the loftiest figures seen in design — the one-off Leica Digital Rangefinder itself designed by Ive and Newson is expected to fetch north of $500,000. Other noteworthy items like a custom “(RED) desk”, original Storm Trooper helmet signed by George Lucas, custom white and red Steinway & Sons piano, space shuttle window from Corning, custom Jaeger-LeCoultre Atmos 561, and several iconic pieces by design favorite Dieter Rams,topped our favorites list. For Apple fans, the rose gold iPhone Earpods and the new Mac Pro in (RED) livery are also in the collection (you can catch a glimpse of the Mac Pro on slide 8). Amassed, they represent a collection of design masterworks. The sale of these incredible goods will help fund the Global Fund to fight against AIDS in Africa.

On a kind invitation from the folks at Sotheby’s, we made our way to a private viewing of the collection before its auction, which happens this Saturday (November 23, 7:00 p.m. EST). You can peruse a full preview of the auction, but our photo essay above represents some of our favorite items.